About

Enterprise experience
meets AI-Native innovation

We've spent decades building enterprise systems. Now we're rebuilding how they get built.

Our Story

Why Brain Stem exists

The Problem We Saw

Enterprise software delivery hasn't fundamentally changed in 20 years. The same lengthy requirements phases. The same bloated quotes. The same "AI-First" vendors delivering the same old solutions at the same old prices.

We knew there had to be a better way.

What We Built

Brain Stem combines battle-tested enterprise expertise with genuine AI-Native methodology. Not AI bolted onto legacy processes, but delivery rebuilt from first principles for the AI era.

The result: faster delivery, lower costs, higher quality.

What we stand for

Speed

Quotes in days, not months. Delivery in weeks, not years.

Quality

Spec-driven development with automated validation at every step.

Transparency

Clear pricing, honest timelines, no hidden surprises.

Partnership

Your success is our success. We're invested in outcomes.

Leadership

Meet the team

Michelle Lock
Michelle Lock
Executive Board Chair

Michelle is a biopharma CEO and Board leader focused on building enterprise value in complex, private equity-backed organisations, particularly during periods requiring clarity, decisive action, and disciplined execution.

Most recently, as CEO and Board Member of Relief Therapeutics, a PE-sponsored public company, she led a strategic reset that narrowed portfolio focus, divested non-core assets, strengthened the leadership team, and realigned the organisation around a defined value pathway — resulting in significant shareholder value creation and a successful company sale.

Previously, as COO and CCO of COVIS Pharma and Head of International at Acceleron (culminating in an $11.4B acquisition), Michelle built and scaled global operating structures, strengthened commercial and development execution, and prepared organisations for IPO and M&A outcomes. Across more than 20 years at Bristol-Myers Squibb, she held senior global clinical, commercial, and general management roles across the US, Europe, Asia, and Australia.

Board & Governance PE-Backed Value Creation $11.4B Acquisition Global Biopharma
Myles Bertrand
Myles Bertrand
Chief Executive Officer

Myles is an experienced senior leader with over 20 years in software solutions, with key strengths in payments, transaction banking, and senior C-level roles. Named one of the Top 50 Fintech CEOs for 2024 by the Financial Technology Report.

Myles has a proven capability to deliver improved customer outcomes through developing product and customer-focused solutions across banking, retail, wealth, insurance, telecommunications and sport. He brings extensive experience managing full P&L at regional and global levels, with a focus on sales, services and support components aligned to business plans.

With leadership roles spanning APAC, Europe and MEA, Myles brings deep global experience in go-to-market strategy, emerging technologies, and AI-driven growth. In his most recent role as CEO at Tuum, he worked closely with the founding team to drive double-digit growth, expansion into new markets, and multiple successful funding rounds.

Top 50 Fintech CEO 2024 Payments & Banking Global P&L APAC / Europe / MEA
Bruce Lock
Bruce Lock
Chief Technology Officer & Founder

With over 30 years of experience in enterprise technology, Bruce has been at the forefront of digital transformation across Australia and Asia-Pacific. His expertise spans cloud infrastructure, enterprise architecture, and strategic technology leadership.

Bruce's proven track record includes establishing technology divisions, leading major digital initiatives, and driving innovation in complex enterprise environments. He founded Brain Stem to revolutionise how enterprise software gets built — combining battle-tested expertise with genuine AI-Native methodology.

30+ Years Enterprise Cloud Infrastructure AI-Native Architecture APAC
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Let's discuss how we can help

Whether you're exploring AI-Native delivery or ready to transform your enterprise software, we'd love to hear from you.

Get in Touch